The resection of the corpus callosum is a surgical technique that was introduced in the past to be able to cure severe forms of epilepsy. Since the corpus callosum is the main communication route between the two hemispheres, its partial or total resection will cause different effects on the brain. This communication is studied through functional magnetic resonance images whose operating principle is based on nuclear magnetic resonance. During the analysis of the subjects, independent components were obtained using the ICA technique, among which, at first, it was possible to identify signal and noise components, subsequently identifying the 10 resting-state networks characterizing brain activity in a state of rest. During this thesis work, some subjects showed a certain bilaterality in the resting state networks, such as the visual network, even after callosotomy surgery.
The resection of the corpus callosum is a surgical technique that was introduced in the past to be able to cure severe forms of epilepsy. Since the corpus callosum is the main communication route between the two hemispheres, its partial or total resection will cause different effects on the brain. This communication is studied through functional magnetic resonance images whose operating principle is based on nuclear magnetic resonance. During the analysis of the subjects, independent components were obtained using the ICA technique, among which, at first, it was possible to identify signal and noise components, subsequently identifying the 10 resting-state networks characterizing brain activity in a state of rest. During this thesis work, some subjects showed a certain bilaterality in the resting state networks, such as the visual network, even after callosotomy surgery.
Analysis of functional connectivity in healthy subjects with intact brain and in patients with surgical resection of the corpus callosum
VITTI, ELENA
2021/2022
Abstract
The resection of the corpus callosum is a surgical technique that was introduced in the past to be able to cure severe forms of epilepsy. Since the corpus callosum is the main communication route between the two hemispheres, its partial or total resection will cause different effects on the brain. This communication is studied through functional magnetic resonance images whose operating principle is based on nuclear magnetic resonance. During the analysis of the subjects, independent components were obtained using the ICA technique, among which, at first, it was possible to identify signal and noise components, subsequently identifying the 10 resting-state networks characterizing brain activity in a state of rest. During this thesis work, some subjects showed a certain bilaterality in the resting state networks, such as the visual network, even after callosotomy surgery.File | Dimensione | Formato | |
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https://hdl.handle.net/20.500.12075/12179